Efficacy/Support Studies

Surface Disinfectants
Sporicidal Surface Disinfectants
Food Contact Sanitizers
High Level Disinfectants
Chemosterilants
Hydrotherapy Tub Disinfectants
Instrument Cleaners & Disinfectants

Food Contact Sanitizers

Assessment of the Sanitizing Action of a Formulation Based on 7% Accelerated Hydrogen Peroxide (AHP) (205 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“When 7% AHP (products sold under Virox 5, Percept, Accel, Peroxigard, Virox and Viper Broad Spectrum No Rinse Sanitizer) is diluted @ 1:128 it is able to bring about a >5Log reduction with a contact time of 30 seconds therefore allowing for a sanitizing claim” pg. 7

Surface Disinfectants

Some Disinfectants Effective Against Feline Calicivirus (as a surrogate for Norovirus) (34 KB): Robert E. Wheeler, MD, FACEP
Excerpt:“AHP (products sold under Virox 5, Percept, Accel, Peroxigard) brought a >4Log reduction against Feline Calicivirus with a 2 minute contact time versus competitive products”
Assessment of the Germicidal Activity of Carpet Cleaners (34 KB): Syed A. Sattar, Ph.D.Professor of Microbiology Centre for Research in Environmental Microbiology (CREM)
The main objective of this study was to determine if the products were bactericidal at full strength or at a 1:16 dilution in standard hard water.
Excerpt:“the products tested show good activity against the two challenge organisms. It required some effort on our part to become familiar with the basic procedure for carpet disinfectant testing and adapted to the materials available.”
Evaluation of the Effectiveness of a 0.5% AHP RTU Against Murine Norovirus (79 KB): Syed A. Sattar, Ph.D.
The objective of this study was to evaluate the virucidal activity of “0.5% AHP RTU” against the Murine norovirus, using protocol #E1053 of ASTM international (2002).
Excerpt:“the test product was able to bring about a >4 log10 reduction in the viability titre of the virus in a contact time of 5 minute at ambient temperature, indicating virucidal activity against this virus. ” pg. 3
Assessment of Accelerated Hydrogen Peroxide for Sanitizing Carpet (137 KB): Daniel Price and Brandi Morris
Excerpt:“The accelerated hydrogen peroxide product along with vacuum extraction effectively removed or inactivated the accumulated biocontaminants. In the laboratory controlled studies against known antibiotic strains the Johnson Diversey Alpha HP product produced 2 to 3 log reductions of the initial bacterial inoculum following a 15 minute dwell time....These products not only clean the surface for aesthetics but also can make the carpet more hygienic by effectively killing or removing biocontaminants.”
Investigative Engineering Report (177 KB): Matthew R. Allen, M.Eng., P.Eng.
Excerpt:“It is apparent that Virox is highly committed to environmental sustainability through its products and operations. Their stance on the issue of Nonylphenol Ethoxylates (NPE) impurities has clearly demonstrated their proactive and due diligent approach and corporate culture (products sold under Virox 5, Percept, Accel, Peroxigard)”
Virucidal Effectiveness Test: Coronavirus (467 KB): M. Khalid Ijaz, DVM, Ph.D.
Excerpt:“AHP (products sold under Virox 5, Percept, Accel, Peroxigard) passed the Virucidal Effectiveness Test when Coronavirus was exposed to the test material for 5 minutes” pg. 10
Stability Of Virox Technologies Inc. Products In The Presence Of Various Levels Of Hard Water Over A Time Frame Of Four Weeks (248 KB): Jose Ramirez, Ph.D. Vice President Research and Development Virox Technologies.
Excerpt:“There is no loss of in peroxide stability after 4 weeks of testing with various levels of hard water (products sold under Virox 5, Percept, Accel, Peroxigard, Perdiem, Hydrox Disinfectant Cleaner)”
Virucidal Effectiveness Test: Human Immunodeficiency Virus Type 1 (296 KB): Viromed Biosafety Laboratories
Excerpt:“Virox 5 (also sold under Percept, Accel, Peroxigard) diluted 1:16 demonstrated complete inactivation of Human Immunodeficiency Virus Type I following a 5 minute contact time”
Virucidal Effectiveness Test: Avian Influenza (H3N2) (333 KB): ATS Labs
Excerpt:“Virox 5 (also sold under Percept, Accel, Peroxigard) diluted 1:16 demonstrated complete inactivation of Avian Influenza A (H3N2) virus following a 5 minute contact time” pg. 12
Assessment of the Microbicidal Activity of an Accelerated Hydrogen Peroxide-based Formulation (AHP-5) Against VRE and MRSA (149 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“Virox AHP-5 (also sold under Virox 5, Percept, Accel, Peroxigard) diluted 1:16 brought about a >6Log reduction in the viability titre of MRSA with a 5 minute contact time and a >5Log reduction in the viability titre of VRE with a 5 minute contact time indicating bactericidal activity against these 2 organisms” pg. 6
Evaluation Of The Activity Of Two Accelerated Hydrogen Peroxide-Based Formulations Against The Spores Of Bacillus Anthracis And Bacillus Subtilis Using A Quantitative Carrier Test (113 KB): Virox Technologies Inc.
Excerpt:“Product labelled AHP 5 (also sold under Virox 5, Percept, Accel, Peroxigard) showed good activity against the spores of B. anthracis and B. subtilis with a 10 minute conact time” pg. 3
Assessment of the Mycobactericidal and Fungicidal Activities of OPTIM 33TB (Canada) (120 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“Optim33TB (also sold under Oxivir TB and Carpe Diem TB) at full strength was able to reduce the viability of M. terrae by >6Log reduction with a one minute contact time and T. mentagrophytes by >5Log reduction in 3 minutes” pg. 5
Assessment of the Germicidal Activity of Accelerated Hydrogen Peroxide Plus (AHP Plus) (464 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“Virox AHP Plus (Accel TB Canada) was able to bring about bactericidal, mycobactericidal, fungicidal and virucidal activities when the product was used at full strength ” pg. 13
Evaluation of the Effectiveness of a 7% Accelerated Hydrogen Peroxide (AHP)-Based Product Against Canine Parvovirus (100 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa
Excerpt:“AHP (sold under Virox 5, Percept, Accel, Peroxigard) diluted 1:16 was able to bring about a >4Log reduction in the viability titre of Canine Parvovirus” pg. 4
Aspergillis niger de-staining study (655 KB): Virox Technologies Inc.
Excerpt:“AHP (sold under Virox 5, Percept, Accel, Peroxigard) @ a 1:12 dilution removed all traces of Aspergillus niger after 2 cleanings” pg. 2
Assessment of the Germicidal Activity of Carpet Cleaners (44 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa
Excerpt:“AHP carpet sanitizers (sold under Upstart and Virox) brought about a 6Log reduction against Staphylococcus aureus & Pseudomonas aeruginosa with a 60 minute contact time” pg. 5
Bactericidal activity of diluted PEROXIGARD (0.5%) against common bacterial fish pathogens after a contact time of 30 seconds (74 KB): Bayotek International Inc.
Excerpt:“Peroxigard has bactericidal activity against common bacterial fish pathogens after a 30 second contact time. Peroxigard has virucidal activity against common viral fish pathogens after a 5 minute contact time”
Evaluation of the Effectiveness of a 0.5% Formulation of Accelerated Hydrogen Peroxide (AHP5) Against Human Rhino Virus Type 14, a Feline Calicivirus and a Human Rotavirus (117 KB): Syed A. Sattar, M.Sc., Dip. Bact., M.S., Ph.D., RM (CCM)
Excerpt:“AHP (Virox 5, Percept, Accel, Peroxigard) was able to bring a >3Log reduction in the viability titre of Human Rhinovirus, Feline Calicivirus, and Human Rotavirus” pg. 5 & 6
Assessment of the Sanitizing Action of a Formulation Based on 7% Accelerated Hydrogen Peroxide (AHP) (205 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“When 7% AHP (products sold under Virox 5, Percept, Accel, Peroxigard, Virox and Viper Broad Spectrum No Rinse Sanitizer) is diluted @ 1:128 it is able to bring about a >5Log reduction with a contact time of 30 seconds therefore allowing for a sanitizing claim” pg. 7
Assessment Of The Germicidal Activity Of 7% Accelerated Hydrogen Peroxide Against Acinetobacter Baumannii Using A Quantitative Carrier Test And A Suspension Test - Diluted At 1:16 (60 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“AHP diluted 1:16 was able to bring about a >6Log reduction against Acinetobacter Baumannii (products sold under Virox 5, Percept, Accel, Peroxigard)"” pg. 6&7
A Product based on accelerated and stabilized hydrogen peroxide: Evidence for broad-spectrum germicidal activity (406 KB): Syed A. Sattar, PhD and V. Susan Springthorpe, M.Sc.
Excerpt:“Accelerated Hydrogen Peroxide (AHP) contains ingredients which are considered safe for humans & benign to the environment. This product has superior cleaning power and increased germicidal potency and has numerous potential applications where cleanup & disinfection are crucial. The product diluted at 1:16 can be used as a general purpose disinfectant (products sold under Virox 5, Percept, Accel, Peroxigard)” pg. 6 & 7
The Significance of a General Virucide Claim Based Upon the Efficacy Against the Polio Virus (44 KB): Therapeutics Products Programme Guidelines: Disinfectant Drugs
Excerpt:“If you do not demonstrate performance against the Polio Virus it is then required that you test and demonstrate performance against specific pathogens (product sold under Virox 5, Percept, Accel, Peroxigard).” pg. 2
Broad-spectrum microbial activity, toxicologic assessment, and materials compatibility of a new generation of accelerated hydrogen peroxide-based environmental surface disinfectant (117 KB): N. Omidbakhsh, B.Sc, Virox Technologies Inc.
Excerpt:“Accel TB (also sold under Oxivir TB, Optim 33TB, Carpe Diem TB) showed a high safety and materials compatibility profile in addition to being a fast acting, intermediate-level disinfectant” pg. 1
Virucidal Efficacy of a Disinfectant for Use on Inanimate Environmental Surfaces Utilizing Duck Hepatitis Virus as a surrogate for Hepatitis B Virus (480 KB): ATS Labs
Excerpt:“in the presence of a 5% horse serum soil load, Accel TB US (also sold under Oxivir TB, Carpe Diem TB and OPTIM 33 TB), ready to use, demonstrated complete inactivation of Duck Hepatitis Virus following a one minute exposure time at 20.2°C as required by the U.S. EPA for virucidal label claims”
Virucidal Efficacy of a Disinfectant for Use on Inanimate Environmental Surfaces Utilizing Bovine Viral Diarrhea as a surrogate for Hepatitis C Virus (509 KB): ATS Labs
Excerpt:“in the presence of a 5% hose serum soil load, Accel TB US (also sold under Oxivir TB, Carpe Diem TB and OPTIM 33 TB ), ready to use, demonstrated complete inactivation of Bovine Viral Diarrhea following a one minute exposure time at 20.0°C as required by the U.S. EPA for virucidal label claims”

Hydrotherapy Tub Disinfectants

Biofilm Testing Report (101 KB): MBEC Biofilm Technologies Inc.
Excerpt:“Virox AHP (products sold under Virox 5, Percept, Accel, Peroxigard) formulation is an effective biocide against Pseudomonas aeruginosa, Streptococcus mutans, Staphylococcus aureus, Salmonella sp. & E. coli with a 30 minute contact time”
Assessment of the Virox Hydrotherapy in the Presence of Butchers Foam Free Defoaming Concentrate (142 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“Virox Hydrotherapy (sold under Accel Hydrotherapy, Virox Hydrotherapy and Turbulence) Product + antifoam was able to bring about a >6Log reduction in the viability titre of Staphylococcus aureus in 5 minutes and a 6Log reduction in 30 seconds therefore indicating its bactericidal activity as a disinfectant and sanitizer ” pg. 6 & 7
Assessment of the Bactericidal and Fungicidal Properties of Accel Hydrotherapy+ (148 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa
Excerpt:“Accel Hydrotherapy+ has been tested in the presence of a 5% soil load and carries a 30-second Broad-Spectrum Sanitizing claim at a 1:128 dilution and 5-minute Bactericidal Claim, 5-Minute General Virucide Claim and 5-minute Fungicidal claim at a 1:16 dilution”
Evaluation of the Effectiveness of Accel Hydrotherapy+ against Poliovirus (127 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa
Excerpt:“Accel Hydrotherapy+ at a dilution of 1:16 was able to bring about a greater than 5 log reduction of the poliovirus at a contact time of 5 minutes” pg. 4

Sporicidal Surface Disinfectants

A New Peroxide-Based Fast Acting Surface Sporocide (167 KB): N. Omidbakhsh, B.Sc, Virox Technologies Inc.
Excerpt:“Accel C.diff Gel is a 4.5% Accelerated Hydrogen Peroxide formulation for disinfection of hard, non-porous surfaces such as toilet bowls, sinks and commodes. Accel C.diff Gel has proven Bactericidal, Fungicidal and Virucidal efficacy in 1-minute and Sporicidal efficacy in 10-minutes”
Assessment of the Broad-Spectrum Microbicidal Activity of Accel C. diff Gel (155 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“Accel C.diff Gel (sold under Rescue Gel) is a 4.5% Accelerated Hydrogen Peroxide formulation for disinfection of hard, non-porous surfaces such as toilet bowls, sinks and commodes. Accel C.diff Gel has proven Bactericidal, Fungicidal and Virucidal efficacy in 1-minute and Sporicidal efficacy in 10-minutes.”

Instrument Cleaners & Disinfectants

KDS Compatibility Project Report (646 KB): Virox Technologies Inc.
Excerpt:“When stainless steel medical equipment was immersed approximately 2 016 times for 5 minutes in KDS diluted 1:16 there were no adverse effects to the instruments”
A New Hydrogen Peroxide - Based Medical-Device Detergent With Germicidal Properties: Comparison With Enzymatic Cleaners (168 KB): Michelle J. Alfa, PhD Michele Jackson, BScb Detroit, Michigan, and Winnipeg, Manitoba, Canada
Excerpt:“KDS has excellent microbial-killing ability in 3-minute exposures and cleans as well as existing enzymatic detergent formulations that were tested and provides a greater protection to HCW's” pg. 168
Assessment of the Germicidal Activity of Killing Detergent Solution (KDS) Using a Quantitative Carrier Test (145 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“KDS diluted @ 1:16 brought a >6Log reduction with a 5 minute contact time against Staphylococcus aureus, Pseudomonas aeruginosa & Salmonella choleraesuis and therefore KDS is considered bactericidal"” pg. 6 & 7

High Level Disinfectants

Microbial Activity of an AHP-Based High Level Disinfectant (PREVENTION and Resert) After 14 Days of Simulated Reuse (142 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“PREVENTION maintained its sporicidal, mycobactericidal & fungicidal activity after 14 days of reuse” pg. 9
A new peroxide-based flexible endoscope-compatible high-level disinfectant (94 KB): N. Omidbakhsh, B.Sc, Virox Technologies Inc.
Excerpt:“AHP-based high-level disinfectant (Accel HLD 5) proved to be a broad spectrum microbicide, fast acting and safer to end users and the environment and is considered compatible with flexible endoscope” pg. 6

Chemosterilants

Combined application of simulated reuse and quantitative carrier tests to assess high-level disinfection: experiments with an accelerated hydrogen peroxide-based formulation (151 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa.
Excerpt:“AHP product (sold under Accel CS 20) represents an alternative to glutaraldehyde with enhanced material compatibility and demonstrates broad-spectrum germicidal activity of a high-level disinfectant subjected 14 days of reuse”
Microbial Activity of Accel CS 20 Chemosterilant and High Level Disinfectant After 14 Days of Simulated Reuse (141 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa
Excerpt:“Accel CS 20 maintained its microbicidal activity after 14 days of reuse” pg. 9
Activity of selected oxidizing microbicides against the spores of Clostridium difficile: Relevances to Environmental Control (172 KB): Syed A. Sattar, Ph.D. Professor of Microbiology Centre for Research in Environmental Microbiology (CREM) Faculty of Medicine, University of Ottawa
Excerpt:“AHP-based technology has been gaining acceptance as a means of formulating safer and environmentally benign microbicides with activity against major classes of nosocomial pathogens. Virox STF could inactivate C difficile spores on hard environmental surfaces in approximately 10-15 minutes under ambient conditions (product sold under Accel CS 20)" ” pg. 5